Studies in the usnic acid series. III. The base catalyzed usnic acid–isousnic acid rearrangement. The synthesis of (+)-isousnic acid
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چکیده
منابع مشابه
Does usnic acid affect microtubules in human cancer cells?
Usnic acid, a lichen metabolite, is known to exert antimitotic and antiproliferative activities against normal and malignant human cells. Many chemotherapy agents exert their activities by blocking cell cycle progression, inducing cell death through apoptosis. Microtubules, protein structure involved in the segregation of chromosomes during mitosis, serve as chemotherapeutical targets due to th...
متن کاملEffect of usnic acid on Candida orthopsilosis and C. parapsilosis.
The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentrati...
متن کاملhistological evaluation of the effect of three medicaments; trichloracetic acid, formocresol and mineral trioxide aggregate on pulpotomized teeth of dogs
چکیده ندارد.
15 صفحه اولData on (+)-usnic acid: A new application to treat toxoplasmosis
Toxoplasma gondii pathogen is a threat to human health that results in economic burden. Unfortunately, there are very few high-efficiency and low-toxicity drugs for toxoplasmosis in the clinic. (+)-Usnic acid derived from lichen species has been reported to have anti-inflammatory, antibacterial, anti-parasitology, and even anti-cancer activities. In associated with the published article "Effect...
متن کاملNtp Nomination for Usnic Acid and Usnea Barbata
What is it? • Usnic acid is a complex polycyclic chemical compound produced naturally by certain lichens species. • Lichens containing usnic acid have been used as traditional medicines and crude drugs in other countries. • Usnic acid as a pure substance has been formulated in creams, toothpaste, mouthwash, deodorants and sunscreen products, either as an active principle or a preservative. FDA ...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1976
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v76-534